Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1912 1
1913 1
1914 1
1923 1
1924 1
1926 2
1927 1
1928 2
1932 1
1934 1
1946 1
1947 4
1948 3
1949 2
1950 8
1951 4
1952 2
1953 9
1954 6
1955 10
1956 6
1957 14
1958 6
1959 6
1960 10
1961 14
1962 17
1963 14
1964 17
1965 15
1966 23
1967 31
1968 18
1969 26
1970 27
1971 26
1972 47
1973 43
1974 59
1975 147
1976 161
1977 138
1978 118
1979 157
1980 165
1981 179
1982 214
1983 252
1984 291
1985 314
1986 328
1987 375
1988 412
1989 472
1990 552
1991 594
1992 722
1993 946
1994 1119
1995 1272
1996 1349
1997 1397
1998 1444
1999 1520
2000 1647
2001 1765
2002 1674
2003 1776
2004 1877
2005 2032
2006 1966
2007 1965
2008 2001
2009 2014
2010 2070
2011 2214
2012 2305
2013 2428
2014 2549
2015 2662
2016 2426
2017 2389
2018 2530
2019 2501
2020 2617
2021 2768
2022 2634
2023 2393
2024 1073

Text availability

Article attribute

Article type

Publication date

Search Results

63,489 results

Results by year

Filters applied: . Clear all
Page 1
The wonderful colors of the hematoxylin-eosin stain in diagnostic surgical pathology.
Chan JK. Chan JK. Int J Surg Pathol. 2014 Feb;22(1):12-32. doi: 10.1177/1066896913517939. Epub 2014 Jan 9. Int J Surg Pathol. 2014. PMID: 24406626 Review.
The hematoxylin-eosin (H&E) stain has stood the test of time as the standard stain for histologic examination of human tissues. ...Extracellular basophilic deposits may be seen in small cell carcinoma and systemic lupus erythematosus, but they differ in that the …
The hematoxylin-eosin (H&E) stain has stood the test of time as the standard stain for histologic examination of human tis …
Labeling nuclear DNA using DAPI.
Chazotte B. Chazotte B. Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.prot5556. doi: 10.1101/pdb.prot5556. Cold Spring Harb Protoc. 2011. PMID: 21205856
Although not as bright as the vital Hoechst stains for DNA, DAPI has greater photostability. It is believed that DAPI associates with the minor groove of double-stranded DNA, with a preference for the adenine-thymine clusters. ...Fluorescence increases approximately 20-fol …
Although not as bright as the vital Hoechst stains for DNA, DAPI has greater photostability. It is believed that DAPI associates with …
Analyzing Cell Death by Nuclear Staining with Hoechst 33342.
Crowley LC, Marfell BJ, Waterhouse NJ. Crowley LC, et al. Cold Spring Harb Protoc. 2016 Sep 1;2016(9). doi: 10.1101/pdb.prot087205. Cold Spring Harb Protoc. 2016. PMID: 27587774
During apoptosis the DNA becomes condensed, but this process does not occur during necrosis. Nuclear condensation can therefore be used to distinguish apoptotic cells from healthy cells or necrotic cells. ...This protocol describes staining and visualization of cell …
During apoptosis the DNA becomes condensed, but this process does not occur during necrosis. Nuclear condensation can therefore be us …
Labeling nuclear DNA with hoechst 33342.
Chazotte B. Chazotte B. Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.prot5557. doi: 10.1101/pdb.prot5557. Cold Spring Harb Protoc. 2011. PMID: 21205857
A number of fluorescent stains are available that label DNA and allow easy visualization of the nucleus in interphase cells and chromosomes in mitotic cells. ...On binding to DNA, the fluorescence greatly increases. This protocol describes the use of Hoechst 33342 to label …
A number of fluorescent stains are available that label DNA and allow easy visualization of the nucleus in interphase cells and chrom …
Cell-death assessment by fluorescent and nonfluorescent cytosolic and nuclear staining techniques.
Atale N, Gupta S, Yadav UC, Rani V. Atale N, et al. J Microsc. 2014 Jul;255(1):7-19. doi: 10.1111/jmi.12133. Epub 2014 May 15. J Microsc. 2014. PMID: 24831993 Review.
Over the years a number of nuclear staining techniques such as propidium iodide, Hoechst-33342, 4', 6-diamidino-2-phenylindole (DAPI), Acridine orange-Ethidium bromide staining, among others have been developed to assess the changes in DNA. Some nonnuclear …
Over the years a number of nuclear staining techniques such as propidium iodide, Hoechst-33342, 4', 6-diamidino-2-phenylindole …
Modified annexin V/propidium iodide apoptosis assay for accurate assessment of cell death.
Rieger AM, Nelson KL, Konowalchuk JD, Barreda DR. Rieger AM, et al. J Vis Exp. 2011 Apr 24;(50):2597. doi: 10.3791/2597. J Vis Exp. 2011. PMID: 21540825 Free PMC article.
The Annexin V/PI protocol is a commonly used approach for studying apoptotic cells. PI is used more often than other nuclear stains because it is economical, stable and a good indicator of cell viability, based on its capacity to exclude dye in living cells. ...Unfo …
The Annexin V/PI protocol is a commonly used approach for studying apoptotic cells. PI is used more often than other nuclear stain
Inception and Development of the Papanicolaou Stain Method.
Chantziantoniou N, Donnelly AD, Mukherjee M, Boon ME, Austin RM. Chantziantoniou N, et al. Acta Cytol. 2017;61(4-5):266-280. doi: 10.1159/000457827. Epub 2017 Apr 7. Acta Cytol. 2017. PMID: 28384641 Free article. Review.
OBJECTIVE: Cytodiagnoses of specific malignancies are enabled through analyses of abnormal nuclear chromatin and cytoplasmic features in stained cells. AIM: The objective of this work was to explore the inception, development, and chemistry of the Pap stain m …
OBJECTIVE: Cytodiagnoses of specific malignancies are enabled through analyses of abnormal nuclear chromatin and cytoplasmic features …
Nuclear and optical dual-labelled imaging agents. Design and challenges.
Singh G, Gott MD, Pietzsch HJ, Stephan H. Singh G, et al. Nuklearmedizin. 2016;55(2):41-50. Nuklearmedizin. 2016. PMID: 27067792 Review.
Within the wide scope of the various imaging techniques, dual-labelled modalities for nuclear (PET, SPECT) and near-infrared fluorescence (NIRF) imaging show promise owing to their comparable detection sensitivity. ...This review focuses on the development of promising dua …
Within the wide scope of the various imaging techniques, dual-labelled modalities for nuclear (PET, SPECT) and near-infrared fluoresc …
DAPI (4',6-diamidino-2-phenylindole) Stains Compact Amyloid Plaques.
Mabrouk R, Gotkiewicz M, Rauramaa T, Tanila H. Mabrouk R, et al. J Alzheimers Dis. 2022;88(3):949-955. doi: 10.3233/JAD-220072. J Alzheimers Dis. 2022. PMID: 35754268
DAPI is conventionally used as a nuclear stain for cells in culture or tissue. Here we demonstrate that it binds specifically to the beta-sheet core of amyloid-beta plaques but not diffuse amyloid-beta at the plaque periphery. ...On the other hand, it provides a han …
DAPI is conventionally used as a nuclear stain for cells in culture or tissue. Here we demonstrate that it binds specifically …
DAPI as a useful stain for nuclear quantitation.
Tarnowski BI, Spinale FG, Nicholson JH. Tarnowski BI, et al. Biotech Histochem. 1991;66(6):297-302. Biotech Histochem. 1991. PMID: 1725854
A simple-to-use fluorescent stain, 4',6-diamidino-2-phenylindole (DAPI), visualizes nuclear DNA in both living and fixed cells. ...Following light microscopic analyses, the stained cells were processed for electron microscopy. Cells stained with DAPI s …
A simple-to-use fluorescent stain, 4',6-diamidino-2-phenylindole (DAPI), visualizes nuclear DNA in both living and fixed cells …
63,489 results
You have reached the last available page of results. Please see the User Guide for more information.